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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAA2
All Species:
34.85
Human Site:
S165
Identified Species:
63.89
UniProt:
P54646
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54646
NP_006243.2
552
62320
S165
F
G
L
S
N
M
M
S
D
G
E
F
L
R
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086410
550
62775
S167
F
G
L
S
N
M
M
S
D
G
E
F
L
R
T
Dog
Lupus familis
XP_546691
722
81319
S335
F
G
L
S
N
M
M
S
D
G
E
F
L
R
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRK8
552
61988
S165
F
G
L
S
N
M
M
S
D
G
E
F
L
R
T
Rat
Rattus norvegicus
Q09137
552
62239
S165
F
G
L
S
N
M
M
S
D
G
E
F
L
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506315
519
59478
S136
F
G
L
S
N
M
M
S
D
G
E
F
L
R
T
Chicken
Gallus gallus
Q9IA88
798
88848
K174
F
G
F
G
N
F
Y
K
S
G
E
P
L
S
T
Frog
Xenopus laevis
NP_001088426
560
64038
A176
F
G
L
S
N
M
M
A
D
G
E
F
L
R
T
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
S207
F
G
F
S
N
L
F
S
R
G
Q
L
L
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623371
515
58559
V139
Y
C
H
R
H
M
I
V
H
R
D
L
K
P
E
Nematode Worm
Caenorhab. elegans
Q95ZQ4
626
70425
T236
F
G
L
S
N
I
M
T
D
G
D
F
L
R
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38997
535
61163
V162
Y
C
H
R
N
M
V
V
H
R
D
L
K
P
E
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
T203
F
G
L
S
N
I
M
T
D
G
N
F
L
K
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
76.4
73.8
N.A.
97.6
98.1
N.A.
71.1
27.3
75.3
22.3
N.A.
N.A.
66.1
53.6
N.A.
Protein Similarity:
100
N.A.
86.7
75.2
N.A.
98.5
99
N.A.
81.1
42.6
85
32.6
N.A.
N.A.
77.7
65.6
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
46.6
93.3
53.3
N.A.
N.A.
6.6
80
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
46.6
100
73.3
N.A.
N.A.
33.3
100
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
44.9
33.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.3
50.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
73.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
93.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
70
0
24
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
62
0
0
0
16
% E
% Phe:
85
0
16
0
0
8
8
0
0
0
0
70
0
0
0
% F
% Gly:
0
85
0
8
0
0
0
0
0
85
0
0
0
0
0
% G
% His:
0
0
16
0
8
0
0
0
16
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
16
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
0
0
16
16
0
% K
% Leu:
0
0
70
0
0
8
0
0
0
0
0
24
85
0
0
% L
% Met:
0
0
0
0
0
70
70
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
93
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
8
0
16
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
16
0
0
0
0
8
16
0
0
0
62
0
% R
% Ser:
0
0
0
77
0
0
0
54
8
0
0
0
0
8
0
% S
% Thr:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
85
% T
% Val:
0
0
0
0
0
0
8
16
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
16
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _